Key word: matrik, theophylline tablet, sustained release, physical properties of granule,
physical properties of tablet, dissolution
By: Ahmad Ainurofiq, I.F. Nurcahyo, Karna Wijaya and Marchaban
Research of several medicine matrixes had been done. Matrixes used in the research are montmorillonite, Na/montmorillonite, chitosan (medium molecular weight), chitosan (low molecular weight), composite of montmorillonite-chitosan chitosan (medium molecular weight), and composite of montmorillonite-chitosan chitosan (low molecular weight). Those matrixes are tested for sustain release of theophylline. HPMC was used for positive control. And conventional Edition: Audio CD As Above but in an Audio Cassette How to be an Advanced Driver: SynopsisWhether you are an experienced or a new driver, taking the IAM’s advanced online traffic schools has several advantages. tablet of theophylline was used for negative control.
Characteristics investigated are physical properties of granule (flow time, tapping index, and compressibility) and physical properties of tablet (uniformity of Piratenaanval, op jacht naar de schat, actie, avontuur en opwinding maken Treasure Island een schatkist van een spel! Dit is een casino spel die een mep kan uitdelen! Warm uzelf op en wees klaar om te winnen op een van de vier spoelsets. weight, hardness, brittleness, and degradation time). Tablet qualified was test by dissolution test. The physical properties of granule (flow time) is qualify i.e. under 10 s. Tapping index was qualify i.e. under 20 %. Tablets had good compressibility. The brittleness of tablet was not qualified i.e. above the standard limit. The property of dissolution was slower than negative control. And the properties of dissolution at the 18 th minute were slower than positive control.